Heterogeneity of plasmids determining high-level resistance to gentamicin in clinical isolates of Streptococcus faecalis
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چکیده
منابع مشابه
Heterogeneity of plasmids determining high-level resistance to gentamicin in clinical isolates of Streptococcus faecalis.
Between November 1981 and October 1984, 48 of 3,458 clinical isolates of Streptococcus faecalis at the University of Michigan Hospital showed high-level (greater than 2,000 micrograms/ml) resistance to gentamicin, as well as to all other clinically available aminoglycosides. Thirteen percent of clinical isolates in the University of Michigan Hospital currently demonstrate this level of resistan...
متن کاملHigh-level resistance to gentamicin in clinical isolates of Streptococcus (Enterococcus) faecium.
During a 14-month period beginning in July 1986, three distinct clinical isolates of Streptococcus (Enterococcus) faecium demonstrating high-level resistance (MIC, greater than 2,000 micrograms/ml) to gentamicin, kanamycin, tobramycin, and streptomycin were recovered from individual patients at one institution. Combinations of ampicillin with any of these agents failed to show bactericidal syne...
متن کاملAssessment of pheromone response in biofilm forming clinical isolates of high level gentamicin resistant Enterococcus faecalis.
Twenty five clinical isolates of high level gentamicin resistant Enterococcus faecalis were tested for their biofilm formation and pheromone responsiveness. The biofilm assay was carried out using microtiter plate method. Two isolates out of the 25 (8%) were high biofilm formers and 19 (76%) and four (16%) isolates were moderate and weak biofilm formers respectively. All the isolates responded ...
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background: enterococci are members of the normal gut flora and released into the environment via sewage outlets, where they can survive for long times. infections with high-level gentamicin resistant (hlgr) enterococci are emerging worldwide. hlgr enterococci have developed a resistance to most antibiotics commonly used for enterococcal infections therefore; treatment of infections caused b...
متن کاملChromosomally mediated high-level gentamicin resistance in Streptococcus mitis.
Four blood culture isolates of Streptococcus mitis were found to be resistant to penicillin (MIC, 16 to 32 micrograms/ml) and gentamicin (MIC, 128 or 1,000 micrograms/ml), and the two antibiotics demonstrated a lack of in vitro synergy. As shown by polymerase chain reaction assays, the structural gene known to encode high-level gentamicin resistance in Enterococcus faecalis, Enterococcus faeciu...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1986
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.30.1.78